0001193125-04-025152 Sample Contracts

GENERAL SECURITY AGREEMENT
General Security Agreement • February 17th, 2004 • Neose Technologies Inc • Medicinal chemicals & botanical products • Pennsylvania

THIS GENERAL SECURITY AGREEMENT, dated as of January 30, 2004, is made by NEOSE TECHNOLOGIES, INC., a Delaware corporation (“Obligor”), to BROWN BROTHERS HARRIMAN & CO., a private bank organized as a partnership (the “Secured Party”).

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RESEARCH, DEVELOPMENT AND LICENSE AGREEMENT BETWEEN NEOSE TECHNOLOGIES, INC. AND NOVO NORDISK A/S DATED AS OF NOVEMBER 17, 2003
Research, Development and License Agreement • February 17th, 2004 • Neose Technologies Inc • Medicinal chemicals & botanical products • Pennsylvania

This RESEARCH, DEVELOPMENT AND LICENSE AGREEMENT (“Agreement”), is dated as of November 17, 2003, between Neose Technologies, Inc., a Delaware corporation (“Neose”), and Novo Nordisk A/S, a Danish corporation (“Novo”).

CREDIT AGREEMENT By and Between BROWN BROTHERS HARRIMAN & CO. and NEOSE TECHNOLOGIES, INC. Dated as of January 30, 2004
Credit Agreement • February 17th, 2004 • Neose Technologies Inc • Medicinal chemicals & botanical products • Pennsylvania

THIS CREDIT AGREEMENT, dated as of January 30, 2004, is between BROWN BROTHERS HARRIMAN & CO., a private bank organized as a partnership (“Bank”), and NEOSE TECHNOLOGIES, INC., a Delaware corporation (“Borrower”).

OPEN-END MORTGAGE AND SECURITY AGREEMENT This Mortgage Secures Future Advances
Open-End Mortgage and Security Agreement • February 17th, 2004 • Neose Technologies Inc • Medicinal chemicals & botanical products

THIS MORTGAGE is dated as of the 30th day of January, 2004 (the “Mortgage”) by and between NEOSE TECHNOLOGIES, INC., a Delaware corporation, with an address of 102 Witmer Road, Horsham, Pennsylvania 19044 (the “Mortgagor”) and BROWN BROTHERS HARRIMAN & CO., a private bank organized as a partnership, with its place of business at 1531 Walnut Street, Philadelphia, Pennsylvania 19102 (the “Mortgagee”).

Portions of this exhibit were omitted and filed separately with the Secretary of the Commission pursuant to an application for confidential treatment filed with the Commission pursuant to Rule 24b-2 under the Securities Exchange Act of 1934. Such...
Neose Technologies Inc • February 17th, 2004 • Medicinal chemicals & botanical products

The purpose of this letter is to amend the Agreement in certain respects to reflect our recent discussions. Capitalized terms used and not otherwise defined in this letter are used as defined in the Agreement.

RESEARCH, DEVELOPMENT AND LICENSE AGREEMENT AMONG NEOSE TECHNOLOGIES, INC. AND NOVO NORDISK A/S AND NOVO NORDISK HEALTH CARE AG DATED AS OF NOVEMBER 17, 2003
Research, Development and License Agreement • February 17th, 2004 • Neose Technologies Inc • Medicinal chemicals & botanical products • Pennsylvania

This RESEARCH, DEVELOPMENT AND LICENSE AGREEMENT (“Agreement”), is dated as of November 17, 2003, among Neose Technologies, Inc., a Delaware corporation (“Neose”), and Novo Nordisk A/S, a Danish corporation, and Novo Nordisk Health Care AG, a Swiss Corporation (collectively, “Novo”).

TERM LOAN NOTE
Neose Technologies Inc • February 17th, 2004 • Medicinal chemicals & botanical products

This Note is the Term Loan Note referred to in the Credit Agreement dated of even date herewith (the “Credit Agreement”) between the Borrower and the Bank, and is entitled to the benefits thereof. Capitalized terms used but not defined herein have the meanings specified in the Credit Agreement.

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