0001193125-03-081884 Sample Contracts

FIRST MODIFICATION TO COMMERCIAL PROMISSORY NOTE
Salix Pharmaceuticals LTD • November 14th, 2003 • Pharmaceutical preparations

THIS FIRST MODIFICATION TO COMMERCIAL PROMISSORY NOTE (“Modification”) is made and entered into this 29th day of September, 2003 by and between SALIX PHARMACEUTICALS, LTD., a Delaware corporation and SALIX PHARMACEUTICALS, INC., a California corporation (collectively, jointly and severally, “Borrower”) and RBC CENTURA BANK (“Bank”).

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