0001178913-19-000965 Sample Contracts

SECOND AMENDMENT AGREEMENT
Amendment Agreement • March 28th, 2019 • BioLineRx Ltd. • Pharmaceutical preparations • Massachusetts

This Amendment Agreement (“Amendment Agreement”), dated as of October 16, 2018 (the “Execution Date”), is between the University of Massachusetts (“University”), a not-for-profit, public institution of higher education of the Commonwealth of Massachusetts, established by Chapter 75 of the Massachusetts General Laws, as represented by its Medical School (Worcester campus), and Agalimmune Ltd (“Company”), a private limited company incorporated in England & Wales (company registration number 08504603) with registered address at 1st Floor Thavies Inn House, 3-4 Holborn Road, London, EC1N 2HA, United Kingdom.

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Contract
License Agreement • March 28th, 2019 • BioLineRx Ltd. • Pharmaceutical preparations • England

[*] Represents material that has been omitted and will be filed separately with the Securities and Exchange Commission pursuant to a request for confidential treatment under Rule 24b-2 of the Securities and Exchange Act of 1934, as amended.

AMENDMENT NO. 1 TO LICENSE AGREEMENT
License Agreement • March 28th, 2019 • BioLineRx Ltd. • Pharmaceutical preparations

THIS AMENDMENT NO. 1 (“Amendment”) is entered into effective as of June 18th, 2018 (the “Amendment Effective Date”) by and between BioLineRx Ltd. (“BioLine”) and Wartner Europe BV (“Perrigo”).

AMENDMENT NO. 1 TO LICENSE AGREEMENT
License Agreement • March 28th, 2019 • BioLineRx Ltd. • Pharmaceutical preparations

THIS AMENDMENT NO. 1 (“Amendment”) is entered into effective as of June 18th, 2018 (the “Amendment Effective Date”) by and between BioLineRx Ltd. (“BioLine”) and Wartner Europe BV (“Perrigo”).

CLINICAL TRIAL COLLABORATION AND SUPPLY AGREEMENT
Collaboration and Supply Agreement • March 28th, 2019 • BioLineRx Ltd. • Pharmaceutical preparations

This Amendment No. 2 to the CLINICAL TRIAL COLLABORATION AND SUPPLY AGREEMENT (this “Amendment No. 2”), made as of the date of last signature hereunder (the “Amendment No. 2 Effective Date”), is by and between Merck Sharp & Dohme B.V. (“Merck”) and BioLineRx Ltd. (“BioLineRx”). Capitalized terms used but not defined herein shall have the meanings ascribed to such terms in the Agreement.

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