0001171843-18-007320 Sample Contracts

AMENDED AND RESTATED AGREEMENT AND PLAN OF MERGER by and among PRECISION THERAPEUTICS INC., Helomics Acquisition, Inc., HELOMICS HOLDING CORPORATION and GERALD J. VARDZEL, JR., AS STOCKHOLDER REPRESENTATIVE Dated as of October 22, 2018
Agreement and Plan of Merger • October 30th, 2018 • Precision Therapeutics Inc. • Orthopedic, prosthetic & surgical appliances & supplies • Delaware

THIS AMENDED AND RESTATED AGREEMENT AND PLAN OF MERGER (this “Agreement”) is made and entered into as of October 22, 2018, by and among Precision Therapeutics, Inc., f/k/a Skyline Medical Inc., a Delaware corporation (“Parent”), Helomics Acquisition, Inc., a Delaware corporation and a wholly owned subsidiary of Parent (“Merger Sub”), Helomics Holding Corporation, a Delaware corporation (the “Company”), and Gerald J. Vardzel, Jr., in his capacity as Stockholder Representative (“Stockholder Representative”). Certain capitalized terms used in this Agreement are defined in Exhibit A.

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