0001171843-16-011779 Sample Contracts

ARGOS THERAPEUTICS, INC. DURHAM, NC 27704
Letter Agreement • August 15th, 2016 • Argos Therapeutics Inc • Pharmaceutical preparations • North Carolina

This letter agreement (the “Agreement”) shall serve to amend and restate the terms and conditions of the employment offer letter dated February 3, 2015 (the “Offer Letter”) between you and Argos Therapeutics, Inc. (“Argos Therapeutics” or the “Company”) in its entirety, and shall become effective as of May 16, 2016 (the “Effective Date”).

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AMENDMENT NO. 2 TO FIFTH AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • August 15th, 2016 • Argos Therapeutics Inc • Pharmaceutical preparations

This Amendment No. 2 (this “Amendment”) to the Fifth Amended and Restated Registration Rights Agreement, dated August 9, 2013 (the “Registration Rights Agreement”), by and among the Company and the Holders (as defined therein) is entered into as of the 14th day of July, 2016 by and among Argos Therapeutics, Inc., a Delaware corporation (the “Company”), and each of the signatories hereto. Capitalized terms not defined herein shall have the meanings given to such terms in the Registration Rights Agreement.

FIFTH AMENDMENT TO LEASE AGREEMENT AND THIRD AMENDMENT TO PURCHASE AND SALE AGREEMENT
Lease Agreement and Third • August 15th, 2016 • Argos Therapeutics Inc • Pharmaceutical preparations

THIS FIFTH AMENDMENT TO LEASE AGREEMENT AND THIRD AMENDMENT TO PURCHASE AND SALE AGREEMENT (this “Omnibus Amendment”), dated effective as of July 1, 2016, by and between TKC LXXII, LLC, a North Carolina limited liability company (“TKC”), and ARGOS THERAPEUTICS, INC., a Delaware corporation (“Argos” and together with TKC, collectively, the “Parties”).

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