0001168197-13-000031 Sample Contracts

AMENDMENT TO PRODUCTION AGREEMENT
Production Agreement • August 9th, 2013 • Liposcience Inc • In vitro & in vivo diagnostic substances

THIS AMENDMENT TO PRODUCTION AGREEMENT (the "Amendment") is made and entered into as of the 1st day of July, 2013 by and among KMC Systems, Inc., a Delaware corporation (“KMC"), and LipoScience, Inc., a Delaware corporation (“LipoScience”).

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FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • August 9th, 2013 • Liposcience Inc • In vitro & in vivo diagnostic substances

THIS FIRST AMENDMENT to Loan and Security Agreement (this “Amendment”) is entered into as of June 11, 2013, by and between OXFORD FINANCE LLC, a Delaware limited liability company with an office located at 133 North Fairfax Street, Alexandria, Virginia 22314 (“Oxford”), as collateral agent (in such capacity, “Collateral Agent”), the Lenders listed on Schedule 1.1 of the Loan Agreement (as defined below) or otherwise party thereto from time to time including Oxford in its capacity as a Lender and SQUARE 1 BANK, a North Carolina banking corporation with an office located at 406 Blackwell Street, Suite 240, Durham, NC 27701 (“Bank” or “Square 1”) (each a “Lender” and collectively, the “Lenders”) and LIPOSCIENCE, INC., a Delaware corporation with offices located at 2500 Sumner Boulevard, Raleigh, NC 27616 (“Borrower”)

LEASE AMENDMENT NO. 4
Liposcience Inc • August 9th, 2013 • In vitro & in vivo diagnostic substances

THIS LEASE AMENDMENT NO. 4 (this "Amendment") is made this 11 day of June 2013 ("Execution Date"), by and between Raleigh Portfolio JH-SBP, LLC (formerly known as Raleigh Portfolio JH, LLC) ("Landlord") and LipoScience, Inc, a Delaware corporation (formerly known as LipoMed, Inc.) ("Tenant").

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