0001159036-17-000015 Sample Contracts

HALOZYME THERAPEUTICS, INC., ISSUER AND [TRUSTEE], TRUSTEE INDENTURE DATED AS OF , 20 SUBORDINATED DEBT SECURITIES
Halozyme Therapeutics Inc • February 28th, 2017 • Biological products, (no disgnostic substances) • New York

Page ARTICLE 1 DEFINITIONS 1 Section 1.01 Definitions of Terms 1 ARTICLE 2 ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 Section 2.01 Designation and Terms of Securities 4 Section 2.02 Form of Securities and Trustee’s Certificate 5 Section 2.03 Denominations: Provisions for Payment 5 Section 2.04 Execution and Authentications 6 Section 2.05 Registration of Transfer and Exchange 7 Section 2.06 Temporary Securities 8 Section 2.07 Mutilated, Destroyed, Lost or Stolen Securities 8 Section 2.08 Cancellation 9 Section 2.09 Benefits of Indenture 9 Section 2.10 Authenticating Agent 9 Section 2.11 Global Securities 10 ARTICLE 3 REDEMPTION OF SECURITIES AND SINKING FUND PROVISIONS 10 Section 3.01 Redemption 10 Section 3.02 Notice of Redemption 10 Section 3.03 Payment Upon Redemption 11 Section 3.04 Sinking Fund 11 Section 3.05 Satisfaction of Sinking Fund Payments with Securities 12 Section 3.06 Redemption of Securities for Sinking Fund 12 ARTICLE 4 COVENANTS 12

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HALOZYME THERAPEUTICS, INC., ISSUER AND [TRUSTEE], TRUSTEE INDENTURE DATED AS OF , 20 SENIOR DEBT SECURITIES
Halozyme Therapeutics Inc • February 28th, 2017 • Biological products, (no disgnostic substances) • New York

Page ARTICLE I DEFINITIONS 1 Section 1.1 Definitions of Terms 1 ARTICLE II ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 Section 2.1 Designation and Terms of Securities 4 Section 2.2 Form of Securities and Trustee’s Certificate 5 Section 2.3 Denominations: Provisions for Payment 5 Section 2.4 Execution and Authentications 6 Section 2.5 Registration of Transfer and Exchange 7 Section 2.6 Temporary Securities 8 Section 2.7 Mutilated, Destroyed, Lost or Stolen Securities 8 Section 2.8 Cancellation 9 Section 2.9 Benefits of Indenture 9 Section 2.10 Authenticating Agent 9 Section 2.11 Global Securities 9 ARTICLE III REDEMPTION OF SECURITIES AND SINKING FUND PROVISIONS 10 Section 3.1 Redemption 10 Section 3.2 Notice of Redemption 10 Section 3.3 Payment Upon Redemption 11 Section 3.4 Sinking Fund 11 Section 3.5 Satisfaction of Sinking Fund Payments with Securities 12 Section 3.6 Redemption of Securities for Sinking Fund 12 ARTICLE IV COVENANTS 12 Section 4.1

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