0001144204-13-051455 Sample Contracts

Protalix BioTherapeutics, Inc. (Company) The Bank of New York Mellon Trust Company, N.A. (Trustee) 4.50% Convertible Senior Notes due 2018 INDENTURE Dated as of September 18, 2013
Indenture • September 18th, 2013 • Protalix BioTherapeutics, Inc. • Biological products, (no disgnostic substances) • New York

INDENTURE, dated as of September 18, 2013, between Protalix BioTherapeutics, Inc., a Florida corporation, as issuer (the “Company”), and The Bank of New York Mellon Trust Company, N.A., as trustee, conversion agent, registrar and paying agent (in such capacities, the “Trustee”, “Conversion Agent”, “Registrar” and “Paying Agent”, respectively).

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60,000,000 4.50% Convertible Notes Due 2018 Purchase Agreement
Purchase Agreement • September 18th, 2013 • Protalix BioTherapeutics, Inc. • Biological products, (no disgnostic substances) • New York

Protalix BioTherapeutics, Inc., a corporation organized under the laws of Florida (the “Company”), proposes to issue and sell to the several parties named in Schedule I hereto (the “Initial Purchasers”), for whom you (the “Representatives”) are acting as representatives, U.S.$60,000,000 principal amount of its 4.50% Convertible Notes due 2018 (the “Firm Securities”). The Company also proposes to grant to the Initial Purchasers an option to purchase up to U.S.$9,000,000 additional principal amount of such Notes, if any (the “Option Securities” and, together with the Firm Securities, the “Securities”). The Securities are convertible into shares of Common Stock, par value U.S.$0.001 per share (the “Common Stock”), of the Company. The Securities are to be issued under an indenture (the “Indenture”), to be dated as of the Closing Date, between the Company and The Bank of New York Mellon, as trustee (the “Trustee”). To the extent there are no additional parties listed on Schedule I other tha

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