0001144204-13-022048 Sample Contracts

Second Amendment to the License Agreement Between the Regents of the University of California and General Fiber, Inc. License Agreement Control No. 2006-04-0026 Effective January 3, 2007
Second Amendment • April 16th, 2013 • Synthetic Biologics, Inc. • Pharmaceutical preparations

This Second Amendment (the “Second Amendment”) dated January 3, 2007 is made by and between The Regents of the University of California and General Fiber, Inc.

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THIRD AMENDMENT TO EXCLUSIVE LICENSE AGREEMENT UC Agreement Control No. 2006-04-0026
Exclusive License Agreement • April 16th, 2013 • Synthetic Biologics, Inc. • Pharmaceutical preparations

This third amendment ("Third Amendment") to the Exclusive License Agreement ("Agreement"), effective August 29, 2007 is made by and between The Regents of the University of California, a California corporation ("The Regents"), and Putney Drug Corp, a Delaware company ("Licensee").

EXCLUSIVE LICENSE AGREEMENT
Exclusive License Agreement • April 16th, 2013 • Synthetic Biologics, Inc. • Pharmaceutical preparations • California

This Agreement is made and is effective this 11th day of July 2005 (the "Effective Date") between THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ("The Regents"), a California corporation having its corporate offices located at 1111 Franklin Street, Oakland, California 94607-5200, acting through its offices located at 10920 Wilshire Blvd, Suite 1200, Los Angeles, California 90024-1406, and General Fiber, Inc ("Licensee"), a corporation having a principal place of business at 801 Brickell Avenue, 9th Floor, Suite 942, Miami, FL 33131.

First Amendment to the License Agreement Between The Regents of the University of California and General Fiber, Inc. UC Agreement Control No. 2006-04-0026
Synthetic Biologics, Inc. • April 16th, 2013 • Pharmaceutical preparations

This First Amendment ("First Amendment"), dated November 08, 2005 (the "Effective Date"), is made by and between The Regents of the University of California ("The Regents") and General Fiber, Inc. ("Licensee").

FOURTH AMENDMENT TO EXCLUSIVE LICENSE AGREEMENT UC Agreement Control No. 2006-04-0026
Exclusive License Agreement • April 16th, 2013 • Synthetic Biologics, Inc. • Pharmaceutical preparations

This fourth amendment (“Fourth Amendment”) to the Exclusive License Agreement (“Agreement”), effective December 31, 2012 is made by and between the Regents of the University of California, a California corporation (“The Regents”), and Putney Drug Corp., a Delaware company (“Licensee”).

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