0001144204-10-068560 Sample Contracts

AMENDMENT TO RIGHTS AGREEMENT BETWEEN SYNTHEMED, INC. AND AMERICAN STOCK TRANSFER & TRUST COMPANY
Rights Agreement • December 28th, 2010 • SyntheMed, Inc. • Orthopedic, prosthetic & surgical appliances & supplies • Delaware

THIS AMENDMENT TO RIGHTS AGREEMENT (the “Amendment”) is made as of the 22nd day of December 2010, by and between SyntheMed, Inc., a Delaware corporation (the “Company”), and American Stock Transfer & Trust Company, LLC, a New York limited liability company (the “Rights Agent”).

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AGREEMENT AND PLAN OF MERGER among: SYNTHEMED, INC., a Delaware corporation; SYMD ACQUISITION SUB, INC., a Massachusetts corporation; and PATHFINDER, LLC, a Massachusetts limited liability company
Agreement and Plan of Merger • December 28th, 2010 • SyntheMed, Inc. • Orthopedic, prosthetic & surgical appliances & supplies • Delaware

THIS AGREEMENT AND PLAN OF MERGER is made and entered into as of December22, 2010, by and among SYNTHEMED, INC. , a Delaware corporation (“SyntheMed”), SYMD ACQUISITION SUB, INC, a newly-formed Massachusetts corporation and a wholly-owned subsidiary of SyntheMed (“Merger Sub”), and PATHFINDER, LLC , a Massachusetts limited liability company (“Pathfinder”). Capitalized terms used in this Agreement are defined in Exhibit A.

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