IONIS PHARMACEUTICALS, INC. AND U.S. BANK NATIONAL ASSOCIATION, as Trustee INDENTURE Dated as of December 19, 2019 0.125% Convertible Senior Notes due 2024Ionis Pharmaceuticals Inc • December 23rd, 2019 • Pharmaceutical preparations • New York
Company FiledDecember 23rd, 2019 Industry JurisdictionINDENTURE dated as of December 19, 2019 between Ionis Pharmaceuticals, Inc., a Delaware corporation, as issuer (the “Company,” as more fully set forth in Section 1.01) and U.S. Bank National Association, a national banking association, as trustee (the “Trustee,” as more fully set forth in Section 1.01).