0001136261-17-000060 Sample Contracts

AMENDMENT NO. 1 TO THE INTERIM SETTLEMENT AGREEMENT BETWEEN PERNIX AND GSK
Pernix Therapeutics Holdings, Inc. • March 21st, 2017 • Pharmaceutical preparations

This AMENDMENT NO. 1 to the interim settlement agreement (this "Amendment"), dated as of March 17, 2017, is entered into by and between Pernix Therapeutics Holdings, Inc. ("Pernix Holdings"), Pernix Ireland Limited ("Pernix Ireland" and together with Pernix Holdings, "Pernix"), on the one hand, and Glaxo Group Limited, GlaxoSmithKline LLC, GlaxoSmithKline Intellectual Property Holdings Limited, and GlaxoSmithKline Intellectual Property Management Limited (collectively, "GSK"), on the other. Each of the foregoing shall be referred to herein as a "Party" and collectively as the "Parties."

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