0001104659-23-090913 Sample Contracts

AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • August 14th, 2023 • Zynerba Pharmaceuticals, Inc. • Pharmaceutical preparations

THIS AMENDMENT (this “Amendment”) to the Employment Agreement by and between Zynerba Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and Armando Anido (“Executive”), originally dated September 4, 2014 and amended on October 2, 2014, and again on August 30, 2019, (the “Employment Agreement”), is made as of August 14, 2023 (the “Effective Date”).

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AGREEMENT AND PLAN OF MERGER by and among HARMONY BIOSCIENCES HOLDINGS, INC., XYLOPHONE ACQUISITION CORP. and ZYNERBA PHARMACEUTICALS, INC. Dated as of August 14, 2023
Agreement and Plan of Merger • August 14th, 2023 • Zynerba Pharmaceuticals, Inc. • Pharmaceutical preparations • Delaware

This Agreement and Plan of Merger (this “Agreement”) is made and entered into as of August 14, 2023, by and among: Harmony Biosciences Holdings, Inc., a Delaware corporation (“Parent”); Xylophone Acquisition Corp., a Delaware corporation and a wholly owned subsidiary of Parent (“Merger Sub”); and Zynerba Pharmaceuticals, Inc., a Delaware corporation (the “Company”). Certain capitalized terms used in this Agreement are defined in Section 1.1.

TENDER AND SUPPORT AGREEMENT
Tender and Support Agreement • August 14th, 2023 • Zynerba Pharmaceuticals, Inc. • Pharmaceutical preparations • Delaware

This Tender and Support Agreement (this “Agreement”) is entered into as of August 14, 2023, by and among Harmony Biosciences Holdings, Inc., a Delaware corporation (“Parent”), Xylophone Acquisition Corp., a Delaware corporation and a wholly owned subsidiary of Parent (“Merger Sub”), and [●] (“Stockholder”).

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