0001104659-18-030238 Sample Contracts

uniQure N.V. 4,500,000 Ordinary Shares (Nominal Value € 0.05 Per Share) UNDERWRITING AGREEMENT
Underwriting Agreement • May 3rd, 2018 • uniQure N.V. • Pharmaceutical preparations • New York

uniQure N.V., a Dutch public company with limited liability (the “Company”), proposes to issue and sell to the several underwriters named in Schedule A (the “Underwriters”) an aggregate of 4,500,000 ordinary shares, nominal value €0.05 per share (the “Ordinary Shares”). The 4,500,000 Ordinary Shares to be sold by the Company are called the “Firm Shares.” In addition, the Company has granted to the Underwriters an option to purchase up to an additional 675,000 Ordinary Shares as provided in Section 2. The additional 675,000 Ordinary Shares to be sold pursuant to such option are called the “Optional Shares.” The Firm Shares and, if and to the extent such option is exercised, the Optional Shares are collectively called the “Offered Shares.” Leerink Partners LLC (“Leerink”) has agreed to act as representative of the several Underwriters (in such capacity, the “Representative”) in connection with the offering and sale of the Offered Shares. To the extent there are no additional underwriters

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