0001104659-16-164590 Sample Contracts

AND [TRUSTEE], Trustee
Axovant Sciences Ltd. • December 30th, 2016 • Pharmaceutical preparations • New York

INDENTURE, dated as of , among AXOVANT SCIENCES LTD., a Bermuda Exempted Limited Company (the “Company”), and [TRUSTEE], as trustee (the “Trustee”):

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AXOVANT SCIENCES LTD. and , AS WARRANT AGENT FORM OF DEBT SECURITIES WARRANT AGREEMENT DATED AS OF
Debt Securities Warrant Agreement • December 30th, 2016 • Axovant Sciences Ltd. • Pharmaceutical preparations • New York

DEBT SECURITIES WARRANT AGREEMENT (this “Agreement”), dated as of between AXOVANT SCIENCES LTD., a Bermuda Exempted Limited Company (the “Company”) and , a [corporation] [national banking association] organized and existing under the laws of and having a corporate trust office in , as warrant agent (the “Warrant Agent”).

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AXOVANT SCIENCES LTD. and , AS WARRANT AGENT FORM OF COMMON SHARE WARRANT AGREEMENT DATED AS OF
Common Share Warrant Agreement • December 30th, 2016 • Axovant Sciences Ltd. • Pharmaceutical preparations • New York

COMMON SHARE WARRANT AGREEMENT (this “Agreement”), dated as of between AXOVANT SCIENCES LTD., a Bermuda Exempted Limited Company (the “Company”) and , a [corporation] [national banking association] organized and existing under the laws of and having a corporate trust office in , as warrant agent (the “Warrant Agent”).

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AXOVANT SCIENCES LTD. and , AS WARRANT AGENT FORM OF PREFERENCE SHARE WARRANT AGREEMENT DATED AS OF
Preference Share Warrant Agreement • December 30th, 2016 • Axovant Sciences Ltd. • Pharmaceutical preparations • New York

PREFERENCE SHARE WARRANT AGREEMENT (this “Agreement”), dated as of between AXOVANT SCIENCES LTD., a Bermuda Exempted Limited Company (the “Company”) and , a [corporation] [national banking association] organized and existing under the laws of and having a corporate trust office in , as warrant agent (the “Warrant Agent”).

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