0001104659-13-061081 Sample Contracts

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. SHARE PURCHASE AGREEMENT BY AND AMONG THE MEDICINES COMPANY, PROFIBRIX B.V., THE EQUITYHOLDERS OF PROFIBRIX B.V. (NAMED...
Share Purchase Agreement • August 7th, 2013 • Medicines Co /De • Pharmaceutical preparations • New York

This Share Purchase Agreement (the “Agreement”) is entered into as of June 4, 2013, by and among The Medicines Company, a Delaware corporation (the “Buyer”); ProFibrix B.V., a limited liability company registered under the laws of the Netherlands with the Trade Register of the Chamber of Commerce under number 28097144 with its statutory seat in Leiderdorp and registered office at Zernikedreef 9, 2333 CK Leiden, the Netherlands (the “Company”); the equityholders of the Company named as sellers on the signature pages attached hereto (collectively, the “Sellers”); the members of the management team of the Company named as warrantors on the signature pages attached hereto (collectively the “Warrantors”); the Option Holders (as defined herein) named on the signature pages attached hereto; and Stichting ProFibrix Sellers Representative, solely in its capacity as the Representative of the Company Equityholders (the “Representative”). The Buyer, the Company, the Sellers and the Representative

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