0001104659-11-014555 Sample Contracts

FIRST SUPPLEMENTAL INDENTURE
First Supplemental Indenture • March 16th, 2011 • Lantheus Medical Imaging, Inc. • Pharmaceutical preparations • New York

FIRST SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated as of March 14, 2011, among Lantheus Medical Imaging, Inc., a Delaware corporation (or its permitted successor) (the “Issuer”), the Guarantors (as defined in the Indenture referred to herein) and Wilmington Trust FSB, as trustee under the Indenture referred to below (the “Trustee”).

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