0001104659-10-051155 Sample Contracts

LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • October 5th, 2010 • Synta Pharmaceuticals Corp • Pharmaceutical preparations • New York

THIS LOAN AND SECURITY AGREEMENT, dated as of September 30, 2010 (as amended, restated, supplemented or otherwise modified from time to time, this “Agreement”) is among GENERAL ELECTRIC CAPITAL CORPORATION (“GECC”), in its capacity as agent for Lenders (as defined below) (together with its successors and assigns in such capacity, “Agent”), the financial institutions who are or hereafter become parties to this Agreement as lenders (together with GECC, collectively the “Lenders”, and each individually, a “Lender”), SYNTA PHARMACEUTICALS CORP., a Delaware corporation (“Borrower”), and the other entities or persons, if any, who are or hereafter become parties to this Agreement as guarantors (each a “Guarantor” and collectively, the “Guarantors”, and together with Borrower, each a “Loan Party” and collectively, “Loan Parties”).

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PLEDGE AGREEMENT
Pledge Agreement • October 5th, 2010 • Synta Pharmaceuticals Corp • Pharmaceutical preparations • New York

This PLEDGE AGREEMENT, dated as of September 30, 2010 (together with all amendments, if any, from time to time hereto, this “Pledge Agreement”) by and among Synta Pharmaceuticals Corp., a Delaware corporation, (“Borrower”), Synta Securities Corp., a Massachusetts corporation (“Guarantor”), (Borrower and Guarantor, together with any other Person that joins this Pledge Agreement as a Pledgor in accordance with Section 27, are collectively the “Pledgors” and each a “Pledgor”) and GENERAL ELECTRIC CAPITAL CORPORATION, a Delaware corporation, in its capacity as Agent for the Lenders (together with any successors, endorsees and assigns, “Agent”).

GUARANTY
Guaranty • October 5th, 2010 • Synta Pharmaceuticals Corp • Pharmaceutical preparations

This GUARANTY (this “Guaranty”), dated as of September 30, 2010 by and among the Guarantors identified as such on the signature page hereof and any persons that join this Guaranty in accordance with Section 5.10 (each, a “Guarantor” and collectively, “Guarantors”), and GENERAL ELECTRIC CAPITAL CORPORATION, a Delaware corporation, individually and as agent (in such capacity and together with any successors, endorsees and assigns, “Agent”) for itself and the lenders from time to time signatory to the Loan Agreement hereinafter defined (“Lenders”).

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