0001104659-05-057570 Sample Contracts

Employment Agreement
Employment Agreement • November 23rd, 2005 • Advanced Life Sciences Holdings, Inc. • Biological products, (no disgnostic substances) • Illinois

THIS EMPLOYMENT AGREEMENT (this “Agreement”) made effective as of the 11th day of April 2005(the “Effective Date”), by and between Advanced Life Sciences, Inc., an Illinois corporation (the “Company”), and David A Eiznhamer, Ph.D. (the “Executive”).

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MASTER SERVICES AGREEMENT
Master Services Agreement • November 23rd, 2005 • Advanced Life Sciences Holdings, Inc. • Biological products, (no disgnostic substances) • North Carolina

This Master Services Agreement (“Agreement”) is made between Advanced Life Sciences, Inc., an Illinois corporation, which has a place of business at 1440 Davey Road, Woodridge, Illinois 60517 (hereinafter “Sponsor”), and Quintiles, Inc., a North Carolina corporation having its principal place of business at 5927 South Miami Boulevard, Morrisville, North Carolina 27560 (hereinafter “Quintiles”). When signed by both parties, this Agreement will set forth the terms and conditions under which Quintiles agrees to provide certain services to Sponsor as set forth herein.

ECG SERVICE AGREEMENT
Ecg Service Agreement • November 23rd, 2005 • Advanced Life Sciences Holdings, Inc. • Biological products, (no disgnostic substances) • Illinois

THIS AGREEMENT is effective as of November 22, 2005 (the “Effective Date”), by and between Covance Cardiac Safety Services Inc., a Wisconsin corporation with offices at 9390 Gateway Drive, Reno, Nevada 89521 (“Covance”) and Advanced Life Sciences, Inc. an Illinois corporation, having its principal place of business at 1440 Davey Road, Woodridge, IL 60517 (“Company”) (this Agreement, as amended, modified or supplemented from time to time being, this “Agreement”).

AUTHORIZATION TO PROCEED WITH: PROTOCOL CL05-001
Proceed Agreement • November 23rd, 2005 • Advanced Life Sciences Holdings, Inc. • Biological products, (no disgnostic substances)

This Authorization to Proceed Agreement (“Agreement”) is between Advanced Life Sciences, Inc., an Illinois corporation located at 1440 Davey Road, Woodridge, IL 60517 (“Customer”) and Quintiles, Inc. located at 5927 South Miami Blvd, Morrisville, NC 27560(“Quintiles”). The parties agree that, while the parties are attempting to negotiate a comprehensive agreement regarding the above-referenced project (the “Project”), Quintiles shall commence, or continue performing, the following activities relating to the Project (the “Services”):

LABORATORY SERVICE AGREEMENT
Laboratory Service Agreement • November 23rd, 2005 • Advanced Life Sciences Holdings, Inc. • Biological products, (no disgnostic substances) • Indiana

This Laboratory Service Agreement (“Agreement”) is effective as of November 22, 2005 (“Effective Date”), by and between Covance Central Laboratory Services LP (“Covance”), an Indiana limited partnership, with offices at 8211 SciCor Drive, Indianapolis, Indiana 46214, and Advanced Life Sciences Inc. (“ALSI”), with offices at 1440 Davey Road, Woodridge, IL 60517.

FIRST AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • November 23rd, 2005 • Advanced Life Sciences Holdings, Inc. • Biological products, (no disgnostic substances)

This FIRST AMENDMENT TO EMPLOYMENT AGREEMENT (this “Amendment”) is entered into as of this 18th day of November, 2005 by and between Advanced Life Sciences, Inc., an Illinois corporation (“ALS”), and Ze-Qi Xu, Ph.D. (the “Executive”) to amend the terms of that certain Employment Agreement dated April 11, 2005 between ALS and the Executive (the “Agreement”).

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