0001104659-05-037892 Sample Contracts

Re: Amendment No. 6 to Toll Manufacturing and Packaging Agreement
Cephalon Inc • August 9th, 2005 • Pharmaceutical preparations

This letter confirms recent discussions regarding the proposed amendment of the Toll Manufacturing and Packaging Agreement dated as of August 24, 1999, as amended by Amendment No. 1 dated July 3, 2001; by Amendment No. 2 dated October 9, 2001; by Amendment No. 3 dated June 21, 2002; by Amendment No. 4 dated April 28, 2003; and by Amendment No. 5 dated August 15, 2003 (collectively, the “Agreement”) by and between Cephalon, Inc. (“Cephalon”) and DSM Pharmaceuticals, Inc. (“DSM”). All terms not otherwise defined herein are used as defined in the Agreement.

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AGREEMENT AND PLAN OF MERGER BY AND AMONG CEPHALON, INC., CEPSAL ACQUISITION CORP., SALMEDIX, INC., DAVID S. KABAKOFF, ARNOLD L. ORONSKY AND PAUL KLINGENSTEIN Dated as of May 12, 2005
Agreement and Plan of Merger • August 9th, 2005 • Cephalon Inc • Pharmaceutical preparations • Delaware

AGREEMENT AND PLAN OF MERGER (this “Agreement“), dated as of May 12, 2005, by and among CEPHALON, INC., a Delaware corporation (“Parent“), CEPSAL ACQUISITION CORP., a Delaware corporation (“Acquisition Corp.“), SALMEDIX, INC., a Delaware corporation (the “Company“) and David S. Kabakoff, an individual, Arnold L. Oronsky, an individual and Paul Klingenstein, an individual, as the Stockholders’ Representatives (solely as to Section 2.5 of this Agreement. Certain capitalized terms used in this Agreement have the meanings ascribed to them in Article X.

SUPPLY AGREEMENT BETWEEN ALKERMES, INC. AND CEPHALON, INC.
Supply Agreement • August 9th, 2005 • Cephalon Inc • Pharmaceutical preparations • Delaware

THIS SUPPLY AGREEMENT (“Agreement”) is made and entered into, effective as of June 23, 2005 (the “Effective Date”), by and between Alkermes, Inc., a Pennsylvania corporation, having a principal place of business at 88 Sidney Street, Cambridge, MA 02139 (“Alkermes”), and Cephalon, Inc., a Delaware corporation having a principal place of business at 41 Moores Road, Frazer, Pennsylvania 19355 (“Cephalon”) (collectively, the “Parties” or individually, a “Party”).

LICENSE AND COLLABORATION AGREEMENT BETWEEN
License and Collaboration Agreement • August 9th, 2005 • Cephalon Inc • Pharmaceutical preparations • Delaware

This License and Collaboration Agreement (the “Agreement”) is entered into effective as of June 23, 2005 (the “Effective Date”) by and between Alkermes, Inc., a Pennsylvania corporation with its principal office at 88 Sidney Street, Cambridge, Massachusetts 02139 (“Alkermes”), and Cephalon, Inc., a Delaware corporation with its principal office at 41 Moores Road, Frazer, Pennsylvania 19355 (“Cephalon”).

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