0001104659-05-035694 Sample Contracts

FIRST AMENDMENT TO AGREEMENT AND PLAN OF MERGER
First Amendment • August 2nd, 2005 • Genaissance Pharmaceuticals Inc • Services-commercial physical & biological research

This First Amendment (the “First Amendment”) to that certain Agreement and Plan of Merger (the “Merger Agreement”), dated as of June 20, 2005, by and among Clinical Data, Inc., a Delaware corporation (“Parent”), Safari Acquisition Corporation, a Delaware corporation and wholly-owned subsidiary of Parent (“Transitory Subsidiary”), and Genaissance Pharmaceuticals, Inc., a Delaware corporation (the “Company”), hereby amends the Merger Agreement effective as of this 28th day of July, 2005, as follows:

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