0001104659-05-029761 Sample Contracts

MASTER SECURITY AGREEMENT
Master Security Agreement • June 27th, 2005 • Acusphere Inc • Pharmaceutical preparations • Virginia

THIS AGREEMENT is between Oxford Finance Corporation (together with its successors and assigns, if any, “Secured Party”) and Acusphere, Inc. (“Debtor”). Secured Party has an office at 133 N. Fairfax Street, Alexandria, VA 22314. Debtor is a corporation organized and existing under the laws of the state of Delaware. Debtor’s mailing address and chief place of business is 500 Arsenal Street, Watertown, MA 02472.

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PROMISSORY NOTE
Acusphere Inc • June 27th, 2005 • Pharmaceutical preparations • Virginia

FOR VALUE RECEIVED, Acusphere, Inc., a Delaware corporation, located at the address stated below (“Maker”) promises, jointly and severally if more than one, to pay to the order of Oxford Finance Corporation or any subsequent holder hereof (each, a “Payee”) at its office located at 133 N. Fairfax Street, Alexandria, VA 22314 or at such other place as Payee or the holder hereof may designate, the principal sum of Dollars ($ ), with interest on the unpaid principal balance, from the date hereof through and including the dates of payment, at a fixed interest rate of percent ( %) per annum, in ( ) consecutive installments of principal and interest as follows:

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