0001104659-05-010003 Sample Contracts

FORM OF MEDIMMUNE, INC. STOCK OPTION AGREEMENT
Stock Option Agreement • March 9th, 2005 • Medimmune Inc /De • Biological products, (no disgnostic substances) • Delaware

STOCK OPTION AGREEMENT (this “Agreement”) dated as of , 20 (the “Date of Grant”) between MedImmune, Inc., a Delaware Corporation (the “Company”) and , (the “Optionee”). Capitalized terms used herein but not defined shall have the meanings attributed to them in the Company’s 2004 Stock Incentive Plan (the “Plan”).

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FORM OF STOCK OPTION AGREEMENT
Stock Option Agreement • March 9th, 2005 • Medimmune Inc /De • Biological products, (no disgnostic substances) • Delaware

STOCK OPTION AGREEMENT (this “Agreement”) dated as of «Date» (the “Date of Grant”) between MedImmune, Inc., a Delaware Corporation (the “Company”) and «LastName» «LastName», (the “Optionee”), which term as used herein shall be deemed to include any successor to the Optionee by will or by the laws of descent and distribution, unless the context shall otherwise require. Capitalized terms used herein but not defined shall have the meanings attributed to them in the 2003 Plan (as defined below).

AMENDMENT NO. 1 TO PART-TIME EMPLOYMENT AGREEMENT
Part-Time Employment Agreement • March 9th, 2005 • Medimmune Inc /De • Biological products, (no disgnostic substances)

This Amendment No. 1 (the “Amendment”), effective as of December 21, 2004 (the “Effective Date”), modifies and amends that certain Part-Time Employment Agreement, dated as of December 31, 2003, by and between Melvin D. Booth (the “Employee”) and MedImmune, Inc. (“MedImmune”).

AMENDED AND RESTATED DISTRIBUTION AGREEMENT
Distribution Agreement • March 9th, 2005 • Medimmune Inc /De • Biological products, (no disgnostic substances) • Maryland

This Amended and Restated Distribution Agreement (“AGREEMENT”) is entered into as of February 23, 2005 (the “EFFECTIVE DATE”) by and between MedImmune, Inc., a Delaware corporation, having its principal place of business at One MedImmune Way, Gaithersburg, MD 20878 (“MEDIMMUNE”), and Abbott International LLC, a Delaware limited liability corporation (“ABBOTT”), having its principal place of business at 100 Abbott Park Road, Abbott Park, IL 60064.

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