0001104659-04-034626 Sample Contracts

PRAECIS PHARMACEUTICALS INCORPORATED Form of Incentive Stock Option Agreement
Incentive Stock Option Agreement • November 9th, 2004 • Praecis Pharmaceuticals Inc • Pharmaceutical preparations • Massachusetts

PRAECIS PHARMACEUTICALS INCORPORATED, a Delaware corporation (the “Company”), hereby grants as of this [DATE], to [NAME] (the “Employee”), an option to purchase a maximum amount of [NUMBER OF SHARES] shares of its common stock, par value $.01 per share (“Common Stock”), at the price of $[EXERCISE PRICE] per share. To the extent the option granted hereby is exercisable pursuant to the terms hereof, such option may be exercised for a period of up to ten years from the date granted. The option granted hereby is subject to the following terms and conditions:

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PRAECIS PHARMACEUTICALS INCORPORATED Form of Non-Qualified Stock Option Agreement
Qualified Stock Option Agreement • November 9th, 2004 • Praecis Pharmaceuticals Inc • Pharmaceutical preparations • Massachusetts

PRAECIS PHARMACEUTICALS INCORPORATED, a Delaware corporation (the “Company”), hereby grants as of this [DATE], to [NAME] (the “Recipient”), an option to purchase a maximum of [NUMBER OF SHARES] shares of its common stock, par value $.01 per share (“Common Stock”), at the price of $[EXERCISE PRICE] per share. To the extent the option granted hereby is exercisable pursuant to the terms hereof, such option may be exercised for a period of up to ten years from the date granted. The option granted hereby is subject to the following terms and conditions:

AMENDMENT NO. 2 dated as of August 30, 2004 (this “Amendment”) TO THE DEVELOPMENT AND SUPPLY AGREEMENT concluded between UCB S.A. and AMGEN INC. (thereafter assigned to PRAECIS PHARMACEUTICALS INCORPORATED) dated June 21, 2000
Development and Supply Agreement • November 9th, 2004 • Praecis Pharmaceuticals Inc • Pharmaceutical preparations

BETWEEN UCB S.A., acting in its own name and on behalf of its affiliated companies, with registered offices at Allée de la Recherche 60, B-1070 Brussels, Belgium, hereinafter “UCB”, on the one hand,

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