0001104659-04-023346 Sample Contracts

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FIRST AMENDMENT TO ACQUISITION AND CONSTRUCTION LOAN AGREEMENT
Acquisition and Construction Loan Agreement • August 9th, 2004 • Praecis Pharmaceuticals Inc • Pharmaceutical preparations

This FIRST AMENDMENT TO ACQUISITION AND CONSTRUCTION LOAN AGREEMENT (this “Amendment”), is made as of the 28th day of June 2004, by and between 830 WINTER STREET LLC, a Delaware limited liability company, having an address of c/o Praecis Pharmaceuticals Incorporated, 830 Winter Street, Waltham, Massachusetts 02451 (“Borrower”) and ANGLO IRISH BANK CORPORATION PLC, with an address at 84 State Street, Boston, Massachusetts 02109 (“Lender”).

FIRST AMENDMENT TO AND REAFFIRMATION OF GUARANTY OF NON-RECOURSE EXCEPTIONS
Praecis Pharmaceuticals Inc • August 9th, 2004 • Pharmaceutical preparations

This FIRST AMENDMENT TO AND REAFFIRMATION OF GUARANTY OF NON-RECOURSE EXCEPTIONS (this “Amendment”), is made as of the 28th day of June, 2004, by and between PRAECIS PHARMACEUTICALS INCORPORATED, a Delaware Corporation (“Guarantor”), with an address at 830 Winter Street, Waltham, Massachusetts 02451 and ANGLO IRISH BANK CORPORATION PLC (“Lender”), with an address at 84 State Street, Boston, Massachusetts 02109.

FIRST AMENDMENT TO AND REAFFIRMATION OF ENVIRONMENTAL COMPLIANCE AND INDEMNITY AGREEMENT
Compliance and Indemnity Agreement • August 9th, 2004 • Praecis Pharmaceuticals Inc • Pharmaceutical preparations

This FIRST AMENDMENT TO AND REAFFIRMATION OF ENVIRONMENTAL COMPLIANCE AND INDEMNITY AGREEMENT (this “Amendment”), is made as of the 28th day of June, 2004, by and between 830 WINTER STREET LLC, a Delaware limited liability company (“Borrower”), PRAECIS PHARMACEUTICALS INCORPORATED, a Delaware corporation (“Guarantor”), each having an address at 830 Winter Street, Waltham, Massachusetts 02451 and Anglo Irish Bank Corporation PLC, with an address at 84 State Street, Boston, Massachusetts 02109 (“Lender”). The Borrower and the Guarantor are sometimes referred to in this Amendment collectively as the “Indemnitors”.

CONFIDENTIAL INFORMATION OMITTED AND FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION. ASTERISKS (*) DENOTE SUCH OMISSIONS. LICENSE, SUPPLY AND DISTRIBUTION AGREEMENT
License, Supply and Distribution Agreement • August 9th, 2004 • Praecis Pharmaceuticals Inc • Pharmaceutical preparations • New York

THIS AGREEMENT is made the April 27, 2004 (the “Effective Date”) by and between PRAECIS PHARMACEUTICALS INCORPORATED, a corporation organized and existing under the laws of State of Delaware having its principal place of business at 830 Winter Street, Waltham, MA 02451, USA (hereinafter referred to as “Praecis”) and SCHERING AG, a corporation organized and existing under the laws of Germany having its principal place of business at 13442 Berlin, Germany (hereinafter referred to as “Schering”). Praecis and Schering are sometimes referred to herein individually as a “Party” and collectively as the “Parties”.

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