0001104659-02-006126 Sample Contracts

Gosse Bruinsma, M.D. Chief Operating Officer
Axonyx Inc • November 14th, 2002 • Pharmaceutical preparations

Reference is made to the Research and License Agreement between New York University (“NYU”) and Axonyx, Inc. (“Corporation”) dated April 1, 1997 (the “License Agreement”). This letter (the “Fourth Amendment”) sets forth our understanding regarding an amendment to the provisions of the License Agreement concerning Axonyx’s Development Plan pursuant to Section 10 and milestone payments pursuant to Section 8 of the License Agreement. Such Amendment will be effective as of the date hereof. Terms which are defined in the License Agreement and the Second and Third Amendments dated March 19, 1999 and February 2000 are used herein as so defined.

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INTELLECTUAL PROPERTY ASSIGNMENT AGREEMENT
Intellectual Property Assignment Agreement • November 14th, 2002 • Axonyx Inc • Pharmaceutical preparations • Victoria
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