0001062993-08-003013 Sample Contracts

Amendment No. 2 to the License Agreement on NTproBNP concluded July 26, 2005
Response Biomedical Corp • July 3rd, 2008 • Services-testing laboratories

WHEREAS, Response Biomedical Corporation, Roche Diagnostics Ltd. and Roche Diagnostics Operations, Inc. have concluded a sales and distribution agreement effective as of June 25, 2008 ("Sales and Distribution Agreement"); and

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ROCHE DIAGNOSTICS, SALES AND DISTRIBUTION AGREEMENT SALES AND DISTRIBUTION AGREEMENT
Distribution Agreement • July 3rd, 2008 • Response Biomedical Corp • Services-testing laboratories • New York

This Supply Agreement (the “Agreement”), effective as of June 25th, 2008 (the “Effective Date”), is by and between Response Biomedical Corporation, a Canadian corporation having its principal place of business at 1781-75th Avenue W., Vancouver, BC V6P 6P2 Canada (the “Supplier”), Roche Diagnostics Ltd, a Swiss corporation having its registered office at Forrenstrasse, 6343 Rotkreuz, Switzerland (“RDR”) and Roche Diagnostics Operations, Inc., a Delaware corporation having its principal place of business at 9115 Hague Road, Indianapolis, Indiana 46250 (“RDO”). RDR, RDO and Supplier are collectively referred to herein as the “Parties” and each individually as a “Party.”

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