0001059790-06-000028 Sample Contracts

September 19, 2006 Re: Collaboration and License Agreement dated as of August 1, 2006 by and between POZEN INC. and Astrazeneca AB (the "Collaboration Agreement") Dear Denise:
Pozen Inc /Nc • November 3rd, 2006 • Pharmaceutical preparations

This letter sets forth the understanding between POZEN INC. (“POZEN”) and Astrazeneca AB (“Astrazeneca”) with regard to the matters set forth below and in connection with the Collaboration Agreement. Any capitalized terms not otherwise defined herein shall have the meaning given such term in the Collaboration Agreement. POZEN and Astrazeneca herein are collectively referred to as the Parties.

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