0001047469-19-003124 Sample Contracts

EMPLOYMENT AGREEMENT
Employment Agreement • May 15th, 2019 • BICYCLE THERAPEUTICS LTD • Pharmaceutical preparations • Massachusetts

This Employment Agreement (“Agreement”) is made between Bicycle Therapeutics, Inc., a Delaware corporation (the “Company”), and Nicholas Keen (the “Executive” and collectively with the Company the “Parties”) and is effective as of (and is conditioned upon) the closing of the first underwritten public offering of the equity securities of Bicycle Therapeutics Limited pursuant to an effective registration statement under the Securities Act of 1933, as amended, occurring on or before June 30, 2019 (the “Effective Date”). This Agreement amends, restates and supersedes the terms of the January 3, 2017, Employment Agreement (the “Prior Agreement”) between the Company and the Executive, except that the Parties acknowledge and agree that Sections 4.3 through 4.15 of the Prior Agreement are not altered by the terms of this Agreement, shall remain in full force and effect and are reproduced for reference in Section 8 herein. Except with respect to Sections 4.3 through 4.15 of the Prior Agreement

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SERVICE AGREEMENT
Service Agreement • May 15th, 2019 • BICYCLE THERAPEUTICS LTD • Pharmaceutical preparations • England and Wales
DATED 15 May 2019 BicycleTX Ltd and Dr Kevin Lee
Agreement • May 15th, 2019 • BICYCLE THERAPEUTICS LTD • Pharmaceutical preparations • England and Wales
EMPLOYMENT AGREEMENT
Employment Agreement • May 15th, 2019 • BICYCLE THERAPEUTICS LTD • Pharmaceutical preparations • Massachusetts

This Employment Agreement (this “Agreement”) is entered into by and between Bicycle Therapeutics Inc., a Delaware corporation (the “Company”), and Peter B. Leone (the “Executive”) as the first date of the Executive’s employment with the Company, which shall be January 28, 2019 unless another date is agreed upon by the Company (the “Effective Date”).

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