0001047469-16-012305 Sample Contracts

Gemphire Therapeutics Inc. UNDERWRITING AGREEMENT
Underwriting Agreement • April 18th, 2016 • Gemphire Therapeutics Inc. • Pharmaceutical preparations • New York
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EMPLOYMENT AGREEMENT
Employment Agreement • April 18th, 2016 • Gemphire Therapeutics Inc. • Pharmaceutical preparations • Michigan

THIS EMPLOYMENT AGREEMENT (this “Agreement”) by and between GEMPHIRE THERAPEUTICS INC., a Delaware corporation (the “Company”) and JEFFREY S. MATHIESEN (the “Executive”) is signed by the Company and the Executive on April 15, 2016, and is made effective as of the IPO Date (the “Effective Date”).

INDEMNIFICATION AGREEMENT Effective Date: , 2016
Indemnification Agreement • April 18th, 2016 • Gemphire Therapeutics Inc. • Pharmaceutical preparations • Delaware

THIS INDEMNIFICATION AGREEMENT (this “Agreement”), is made as of the Effective Date set forth above, between GEMPHIRE THERAPEUTICS INC., a Delaware corporation (the “Company”), whose address is 43334 Seven Mile Road, Suite 1000, Northville, Michigan 48167, and [INSERT NAME] (“Indemnitee”).

GEMPHIRE THERAPEUTICS INC. FORM OF NOTE PURCHASE AGREEMENT JOINDER AGREEMENT
Joinder Agreement • April 18th, 2016 • Gemphire Therapeutics Inc. • Pharmaceutical preparations

THIS JOINDER AGREEMENT (this “Joinder Agreement”) is made as of December , 2015, by and among GEMPHIRE THERAPEUTICS INC., a Delaware corporation (the “Company”), and the individual or entity listed on the signature page attached hereto (the “Purchaser”).

FORM OF NOTE PURCHASE AGREEMENT
Note Purchase Agreement • April 18th, 2016 • Gemphire Therapeutics Inc. • Pharmaceutical preparations • Michigan

This Note is issued pursuant to the terms of that certain Note Purchase Agreement, dated as of July 31, 2015 (the “Note Purchase Agreement”), among the Company and, among others, the Holder and is entitled to the benefit thereof. Capitalized terms used herein without definition shall have the respective meanings ascribed to them in the Note Purchase Agreement.

GEMPHIRE THERAPEUTICS INC. INVESTOR RIGHTS AGREEMENT
Investor Rights Agreement • April 18th, 2016 • Gemphire Therapeutics Inc. • Pharmaceutical preparations • Michigan

THIS INVESTOR RIGHTS AGREEMENT (this “Agreement”) is entered into as of March 31, 2015 by and among GEMPHIRE THERAPEUTICS INC., a Delaware corporation (the “Company”), and the Investors listed on EXHIBIT A attached to this Agreement (collectively, the “Investors” and each, without distinction among them, an “Investor”).

OFFICE SPACE SUBLEASE AGREEMENT
Office Space Sublease Agreement • April 18th, 2016 • Gemphire Therapeutics Inc. • Pharmaceutical preparations • Michigan

This OFFICE SPACE SUBLEASE AGREEMENT (this “Agreement”) is dated and effective as of January 1, 2015 (“Effective Date”), by and MICHIGAN LIFE VENTURES, LLC a Michigan limited liability company with offices located at 43334 Seven Mile Road, Suite 100, Northville, MI 48167 (“MLV”), and, Gemphire Therapeutics Inc. a Delaware corporation with offices located at 43334 Seven Mile Road, Suite 1000, Northville, MI 48167 (“GEMPHIRE”).

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