0001047469-13-010435 Sample Contracts

Alkermes plc Ordinary Shares Preferred Shares Debt Securities Form of Underwriting Agreement
Alkermes Plc. • November 12th, 2013 • Pharmaceutical preparations • New York

Alkermes plc (the “Company”), a company incorporated under the laws of Ireland, proposes to sell to the several underwriters named in Schedule I hereto (the “Underwriters”), for whom you (the “Representatives”) are acting as representatives, [ ] ordinary shares, par value $0.01 per share (the “Ordinary Shares”) and/or [ ] preferred shares, par value $0.01 per share (the “Preferred Shares”) and/or $[ ] principal amount of debt securities (the “Debt Securities” and, collectively with the Ordinary Shares and the Preferred Shares, the “Securities”) of the Company. To the extent there are no additional Underwriters listed on Schedule I other than you, the term Representatives as used herein shall mean you, as Underwriters, and the terms Representatives and Underwriters shall mean either the singular or plural as the context requires. The use of the neuter in this Agreement shall include the feminine and masculine wherever appropriate. Certain terms used herein are defined in Section 22 here

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INDENTURE Dated as of [Date] Between ALKERMES PLC, as Company and [TRUSTEE], as Trustee DEBT SECURITIES
Indenture • November 12th, 2013 • Alkermes Plc. • Pharmaceutical preparations • New York

INDENTURE dated as of [Date], between ALKERMES PLC, a corporation incorporated under the laws of the Republic of Ireland (the “Company”), and [TRUSTEE], a [national banking association], as trustee (the “Trustee”).

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