0001047469-12-007287 Sample Contracts

Shares STEMLINE THERAPEUTICS, INC. Common Stock UNDERWRITING AGREEMENT
Underwriting Agreement • July 19th, 2012 • Stemline Therapeutics Inc • Pharmaceutical preparations • New York

Stemline Therapeutics, Inc., a Delaware corporation (the “Company”), proposes, subject to the terms and conditions contained herein, to sell to you and the other underwriters named on Schedule I to this Agreement (the “Underwriters”), for whom you are acting as Representative (the “Representative”), an aggregate of shares (the “Firm Shares”) of the Company’s common stock, $0.0001 par value per share (the “Common Stock”). The respective amounts of the Firm Shares to be purchased by each of the several Underwriters are set forth opposite their names on Schedule I hereto. In addition, the Company proposes to grant to the Underwriters an option to purchase up to an additional shares (the “Option Shares”) of Common Stock from the Company for the purpose of covering over-allotments in connection with the sale of the Firm Shares. The Firm Shares and the Option Shares are collectively called the “Shares.”

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STEMLINE THERAPEUTICS, INC. Incentive Stock Option Agreement Granted Under 2012 Equity Incentive Plan NOTICE OF GRANT
Incentive Stock Option Agreement • July 19th, 2012 • Stemline Therapeutics Inc • Pharmaceutical preparations

Stemline Therapeutics, Inc., a Delaware corporation (the “Company”), pursuant to its 2012 Equity Incentive Plan, as amended from time to time (the “Plan”), hereby grants to the Participant listed below (“Participant”), an option to purchase the number of Shares (as defined in the Plan) set forth below (the “Option”). This Option is subject to all of the terms and conditions set forth herein and in the Incentive Stock Option Agreement attached hereto as Exhibit A (the “Stock Option Agreement”) and the Plan, each of which are incorporated herein by reference. Capitalized terms used but not otherwise defined in this Notice of Grant shall have the meanings ascribed to them in the Plan or the Stock Option Agreement.

STEMLINE THERAPEUTICS, INC. Nonstatutory Stock Option Agreement Granted Under 2012 Equity Incentive Plan NOTICE OF GRANT
Nonstatutory Stock Option Agreement • July 19th, 2012 • Stemline Therapeutics Inc • Pharmaceutical preparations

Stemline Therapeutics, Inc., a Delaware corporation (the “Company”), pursuant to its 2012 Equity Incentive Plan, as amended from time to time (the “Plan”), hereby grants to the Participant listed below (“Participant”), an option to purchase the number of Shares (as defined in the Plan) set forth below (the “Option”). This Option is subject to all of the terms and conditions set forth herein and in the Nonstatutory Stock Option Agreement attached hereto as Exhibit A (the “Stock Option Agreement”) and the Plan, each of which are incorporated herein by reference. Capitalized terms used but not otherwise defined in this Notice of Grant shall have the meanings ascribed to them in the Plan or the Stock Option Agreement.

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