0001047469-06-014650 Sample Contracts

• Shares AFFYMAX, INC. COMMON STOCK, PAR VALUE $0.001 PER SHARE UNDERWRITING AGREEMENT
Underwriting Agreement • November 30th, 2006 • Affymax Inc • Pharmaceutical preparations • New York

Morgan Stanley & Co. Incorporated Cowen and Company, LLC Thomas Weisel Partners LLC RBC Capital Markets c/o Morgan Stanley & Co. Incorporated 1585 Broadway New York, NY 10036

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Attn: Robert Naso, Ph.D., Executive Vice President, R&D Re: Sixth Extension of Letter Agreement Dear Bob:
Affymax Inc • November 30th, 2006 • Pharmaceutical preparations
Fifth Extension of Letter Agreement Dear Bob:
Letter Agreement • November 30th, 2006 • Affymax Inc • Pharmaceutical preparations
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