0001047469-05-009447 Sample Contracts

CONSULTING AGREEMENT
Consulting Agreement • April 7th, 2005 • Gentium S.p.A. • Pharmaceutical preparations

This Consulting Agreement ("Agreement") is by and between KKS-UKT, gGmbH, a German Corporation ("KKS"), located at Otfried-Müller-Str. 45, 72076 Tübingen, Germany, and Gentium, an Italy Corporation ("Gentium"), located at Piazza XX Settembre 2, Villa Gardia (Como), Italy.

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GENERAL CONSULTING AGREEMENT
Consulting Agreement • April 7th, 2005 • Gentium S.p.A. • Pharmaceutical preparations • New Jersey

This Consulting Agreement ("Agreement") is by and between Bradstreet Clinical Research & Associates, Inc., a New Jersey Corporation ("Bradstreet"), located at 1588 Route 130 North, Suite C-2, North Brunswick, NJ, 08902, and Gentium, an Italy Corporation ("Gentium"), located at Piazza XX Settembre, 2, 22079 Villa Guardia (CO), Italy, Villa Gardia (Como), Italy.

INVESTORS' RIGHTS AGREEMENT
Rights Agreement • April 7th, 2005 • Gentium S.p.A. • Pharmaceutical preparations • New York

THIS INVESTORS' RIGHTS AGREEMENT is made as of the 4th day of April, 2005, by and between Gentium S.p.A., a joint stock company (società per azioni) incorporated and organized under the laws of the Republic of Italy (the "Company"), on the one hand, and Sigma Tau Finanziaria S.p.A., a corporation incorporated under the laws of Italy ("Sigma Tau"), on the other hand.

SUBSCRIPTION AGREEMENT
Subscription Agreement • April 7th, 2005 • Gentium S.p.A. • Pharmaceutical preparations • New York

SUBSCRIPTION AGREEMENT (this "Agreement") made as of the date set forth on the signature page hereof between Gentium S.p.A., a joint stock company (societá per azioni) incorporated and organized under the laws of the Republic of Italy having a place of business at Piazza XX Settembre, n. 2, 22079 Villa Guardia, Como, Italy (the "Company"), and the undersigned (the "Subscriber").

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