0001047469-03-021964 Sample Contracts

BIOSEARCH ITALIA, S.P.A. AND GENOME THERAPEUTICS CORPORATION LICENSE AND SUPPLY AGREEMENT
License and Supply Agreement • June 23rd, 2003 • Vicuron Pharmaceuticals Inc • Pharmaceutical preparations • New York

THIS LICENSE AND SUPPLY AGREEMENT (the “Agreement”) is made effective as of the 8th day of October, 2001 (the “Effective Date”) by and between GENOME THERAPEUTICS CORPORATION a Massachussetts corporation having its principal place of business at 100 Beaver Street, Waltham, MA 02453, USA (“GENE”) and BIOSEARCH ITALIA, S.p.A. an Italian corporation with its principal place of business at via R. Lepetit, 34, 21040 Gerenzano, Italy (“Biosearch”). GENE and Biosearch are sometimes referred to herein individually as a “Party”and collectively as the “Parties.”

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AMENDMENT NO. 1 TO LICENSE AND SUPPLY AGREEMENT
License and Supply Agreement • June 23rd, 2003 • Vicuron Pharmaceuticals Inc • Pharmaceutical preparations • New York

This AMENDMENT NO. 1 TO THE LICENSE AND SUPPLY AGREEMENT (this “Amendment”) dated as of August 8, 2002 is entered into by and between GENOME THERAPEUTICS CORP., a Massachusetts corporation having its principal place of business at 100 Beaver Street, Waltham, MA 02453, USA (“GENE”) and BIOSEARCH ITALIA, S.p.A. with its principal place of business at via R. Lepetit, 34, 21040, Gerenzano, Italy (“Biosearch”).

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