0001047469-03-006710 Sample Contracts

CORVAS INTERNATIONAL, INC. FIRST AMENDMENT TO RIGHTS AGREEMENT
Rights Agreement • February 25th, 2003 • Corvas International Inc • Pharmaceutical preparations

THIS FIRST AMENDMENT TO RIGHTS AGREEMENT (this "Amendment") is made as of February 24, 2003 between CORVAS INTERNATIONAL, INC., a Delaware corporation (the "Company"), and AMERICAN STOCK TRANSFER AND TRUST COMPANY (the "Rights Agent").

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Lock-Up And Voting Agreement
Up and Voting Agreement • February 25th, 2003 • Corvas International Inc • Pharmaceutical preparations • Delaware

This Lock-up and Voting Agreement, dated as of February 24, 2003, (this "Agreement"), is by and among Dendreon Corporation, a Delaware corporation ("Dendreon"), and the stockholder of Corvas International, Inc., a Delaware corporation ("Corvas") whose signature appears on the signature pages hereof (a "Corvas Stockholder"). All capitalized terms used herein without definition having the respective meanings ascribed to them in the Merger Agreement (as defined below).

Lock-Up And Voting Agreement
Up and Voting Agreement • February 25th, 2003 • Corvas International Inc • Pharmaceutical preparations • Delaware

This Lock-up and Voting Agreement, dated as of February 24, 2003, (this "Agreement"), is by and among Corvas International, Inc., a Delaware corporation ("Charger"), and the stockholder of Dendreon Corporation, a Delaware corporation ("Dendreon") whose signature appears on the signature pages hereof (a "Dendreon Stockholder"). All capitalized terms used herein without definition having the respective meanings ascribed to them in the Merger Agreement (as defined below).

AGREEMENT AND PLAN OF MERGER
Agreement and Plan of Merger • February 25th, 2003 • Corvas International Inc • Pharmaceutical preparations • Delaware

THIS AGREEMENT AND PLAN OF MERGER (the "Agreement"), dated February 24, 2003, is by and among DENDREON CORPORATION, a Delaware corporation, ("Dendreon"), SEAHAWK ACQUISITION, INC., a Delaware corporation and a wholly owned subsidiary of Dendreon ("Sub"), CHARGER PROJECT LLC, a Delaware limited liability company of which Dendreon is the sole member ("LLC") and CORVAS INTERNATIONAL, INC., a Delaware corporation, ("Corvas").

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