0000950170-23-020079 Sample Contracts

SYNEOS HEALTH, INC. 2018 Equity Incentive Plan Global Restricted Stock Unit Award Agreement
Global Restricted Stock Unit Award Agreement • May 10th, 2023 • Syneos Health, Inc. • Services-commercial physical & biological research • Colorado

The RSUs are an extraordinary benefit, which for labor law purposes (e.g., thirteenth month salary, Christmas bonuses, or similar payments) are valued at the fair market value of the Shares on the date of vesting, when the Shares are delivered to the Participant. Such value is inclusive of thirteenth month salary for the month in which the vesting occurs.

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SIXTH SUPPLEMENTAL INDENTURE
Sixth Supplemental Indenture • May 10th, 2023 • Syneos Health, Inc. • Services-commercial physical & biological research

Sixth Supplemental Indenture (this “Supplemental Indenture”), dated as of February 24, 2023, among the undersigned Subsidiary (the “Guaranteeing Subsidiary”), a subsidiary of Syneos Health, Inc. (or its permitted successor), a Delaware corporation (the “Company”), the Company, the other Guarantors (as defined in the Indenture referred to herein) and Computershare Trust Company, National Association (as successor to Wells Fargo Bank, National Association), as trustee under the Indenture referred to below (the “Trustee”).

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