MERRILL LYNCH CAPITAL, a division of Merrill Lynch Business Financial Services Inc. 222 N. LaSalle Street, 16th Floor Chicago, IL 60601 August 30, 2007Isotis Inc • August 31st, 2007 • Services-commercial physical & biological research
RE: Credit and Security Agreement dated as of May 29, 2007 (as amended, restated, replaced, supplemented or otherwise modified from time to time, the “Credit Agreement”) by and among ISOTIS, INC., a Delaware corporation, and ISOTIS ORTHOBIOLOGICS, INC., a Washington corporation, and any additional Borrower from time to time parties thereto (collectively, “Borrowers”), the various financial institutions from time to time parties thereto as Lenders and MERRILL LYNCH CAPITAL, a division of Merrill Lynch Business Financial Services Inc., as Administrative Agent, Sole Lead Arranger and Sole Bookrunner
