0000950135-08-001703 Sample Contracts

Altus Pharmaceuticals Inc. February 4, 2008
Letter Agreement • March 11th, 2008 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • Massachusetts

The purpose of this letter agreement (the “Agreement”) is to set forth the terms of your resignation from Altus Pharmaceuticals Inc. (the “Company”). Payment of the Separation Pay described below is contingent on your agreement to and compliance with the terms of this Agreement. Neither this offer to you nor the Company’s entering into this Agreement shall constitute an admission by the Company.

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TERMINATION AND TRANSITION AMENDMENT TO THE COLLABORATION AND LICENSE AGREEMENT
Collaboration and License Agreement • March 11th, 2008 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances)

THIS Amendment (the “Amendment”) to the Collaboration and License Agreement by and between Altus Pharmaceuticals, Inc. (“Altus”) and Genentech, Inc. (“Genentech”) dated December 19, 2006 (the “Agreement”) is made and entered into by Altus and Genentech effective as of December 19, 2007 (the “Amendment Effective Date”). Altus and Genentech may each be referred to as a “Party” or together, the “Parties”.

MANUFACTURING LICENSE, OPTION AND SUPPORT AGREEMENT between AMANO ENZYME, INC. and ALTUS PHARMACEUTICALS INC. PORTIONS OF THIS EXHIBIT WERE OMITTED AND HAVE BEEN FILED SEPARATELY WITH THE SECRETARY OF THE COMMISSION PURSUANT TO THE COMPANY’S...
License, Option and Support Agreement • March 11th, 2008 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances)

MANUFACTURING LICENSE, OPTION AND SUPPORT AGREEMENT dated as of December 20, 2007 (the “Effective Date”) between AMANO ENZYME, INC., a corporation organized and existing under the laws of Japan, having its principal place of business at 1-2-7, Nishiki, Naka-ku, Nagoya, Japan (hereinafter referred to as “Amano”) and ALTUS PHARMACEUTICALS INC., a Delaware corporation having its principal place of business at 125 Sidney Street, Cambridge, Massachusetts 02110, USA (hereinafter referred to as “Altus”).

EMPLOYMENT AGREEMENT
Employment Agreement • March 11th, 2008 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • Massachusetts

THIS EMPLOYMENT AGREEMENT (the “Agreement”), is made as of this 4th day of February, 2008, between David Pendergast (“Executive Chairman”) and Altus Pharmaceuticals Inc. (the “Company”).

ALTUS PHARMACEUTICALS INC. NON-QUALIFIED STOCK OPTION AGREEMENT
Non-Qualified Stock Option Agreement • March 11th, 2008 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • Delaware
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