0000950135-06-003276 Sample Contracts

CONSULTING AGREEMENT
Consulting Agreement • May 8th, 2006 • EPIX Pharmaceuticals, Inc. • In vitro & in vivo diagnostic substances • Massachusetts

This Agreement is made as of the date written above (the “Effective Date”) between EPIX Pharmaceuticals, Inc. a Delaware corporation having a usual place of business at 161 First Street, Cambridge, Massachusetts 02142 (the “Company”) and Michael J. Astrue (“you”). This Agreement confirms our understanding with respect to (i) you rendering services as a consultant to the Company, and (ii) you agreeing to protect and preserve information and property which is confidential and proprietary to the Company or other third parties with whom the Company does business. The Company and you both acknowledge that (a) you resigned your employment as the Company’s Chief Executive Officer (“CEO”) effective May 5, 2006, (b) you have received all compensation due to you relating to your employment with EPIX and the termination thereof, and (c) you will not be providing services as CEO pursuant to this Agreement and do not wish to have any employment relationship with EPIX going forward.

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