0000950134-06-019502 Sample Contracts

PROMISSORY NOTE AND SECURITY AGREEMENT
Promissory Note and Security Agreement • October 24th, 2006 • Aradigm Corp • Electromedical & electrotherapeutic apparatus • New York

FOR VALUE RECEIVED, ARADIGM CORPORATION, a California corporation (with its successors, the “Borrower”), promises to pay to the order of NOVO NORDISK A/S (the “Lender”) at its office at Novo Allé 1, DK-2880 Bagsværd, Denmark, in lawful money of the United States of America in same day funds, US$7,500,000 (the “Loan”; and this Promissory Note and Security Agreement, as amended from time to time, the “Agreement”), in accordance with the payment schedule attached hereto. The Loan shall mature on June 30, 2014. Interest shall accrue on the unpaid principal amount of the Loan until maturity on the dates and at a rate per annum as hereinafter set forth. Interest hereunder shall be computed on the basis of a year of 360 days and paid for the actual number of days elapsed (including the first day but excluding the last day).

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ASSET PURCHASE AGREEMENT BY AND BETWEEN ARADIGM CORPORATION. AND SJ2 THERAPEUTICS, INC. Dated as of August 25, 2006
Asset Purchase Agreement • October 24th, 2006 • Aradigm Corp • Electromedical & electrotherapeutic apparatus • California

THIS ASSET PURCHASE AGREEMENT (this “Agreement”) is made and entered into as of August 25, 2006 by and between Aradigm Corporation, a California corporation (“Aradigm”), and SJ2 Therapeutics, Inc., a Delaware corporation (“Purchaser”). Aradigm and Purchaser are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

AMENDED AND RESTATED STOCK PURCHASE AGREEMENT ARADIGM CORPORATION January 26, 2005
Stock Purchase Agreement • October 24th, 2006 • Aradigm Corp • Electromedical & electrotherapeutic apparatus • California

This Amended and Restated Stock Purchase Agreement (the “Agreement”) is made and entered into as of January 26, 2005, by and among Aradigm Corporation, a corporation duly organized and existing under the law of the State of California (“Aradigm”), Novo Nordisk A/S, a company organized and existing under the Law of Denmark (“Novo Nordisk”) and Novo Nordisk Pharmaceuticals, Inc. a corporation duly organized and existing under the law of the State of Delaware (“Novo Nordisk Pharmaceuticals, Inc.”).

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