0000950123-21-016572 Sample Contracts

AMENDMENT NO. 2 TO THE LICENSE AGREEMENT BETWEEN INTRINSIC MEDICINE, INC. (FKA LUPA BIO, INC.) AND THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
The License Agreement • December 30th, 2021 • Intrinsic Medicine, Inc. • Biological products, (no disgnostic substances)

This Amendment No. 2 to the License Agreement (this “Amendment No. 2”) is entered into by and between Intrinsic Medicine, Inc. (fka Lupa Bio, Inc.) (hereinafter “LICENSEE”) and the Regents of the University of California (“UNIVERSITY”) represented by its San Diego campus (“UC San Diego”), each referred to herein as a “Party”, or collectively as the “Parties”. Capitalized terms used herein and not otherwise defined have the meanings ascribed to them in the License Agreement.

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LICENSE AGREEMENT
License Agreement • December 30th, 2021 • Intrinsic Medicine, Inc. • Biological products, (no disgnostic substances) • California

This agreement (“Agreement”) is entered into as of the date of last signature (the “Effective Date”) by and between Lupa Bio, Inc. a Delaware corporation having an address at 320 Acacia Avenue, Unit G, Carlsbad, California 92008 (“LICENSEE”) and The Regents of the University of California, a California public corporation having its statewide administrative offices at 1111 Franklin Street, Oakland, California 94607-5200 (“UNIVERSITY”), represented by its San Diego campus having an address at University of California, San Diego, Office of Innovation and Commercialization, Mail Code 0910, 9500 Gilman Drive, La Jolla, California 92093-0910 (“UC SAN DIEGO”).

LICENSE AND SUPPLY AGREEMENT BY AND BETWEEN GLYCOSYN, LLC AND LUPA BIO, INC.
License and Supply Agreement • December 30th, 2021 • Intrinsic Medicine, Inc. • Biological products, (no disgnostic substances) • Massachusetts

THIS EXCLUSIVE LICENSE, CLINICAL SUPPLY AND PARTNERSHIP AGREEMENT (the “Agreement”) made and entered into as of July 30, 2020 (the “Effective Date”), by and between GLYCOSYN LLC (“Glycosyn”) at 890 Winter Street, Suite 208, Waltham, MA 02451 and LUPA BIO, INC. (“Lupa Bio”) at [***], Glycosyn and Lupa Bio are hereinafter referred to individually as a “Party” and jointly as “Parties.”

RESEARCH AND DEVELOPMENT COLLABORATION AGREEMENT BETWEEN ARPEGGIO BIOSCIENCES AND INTRINSIC MEDICINE
Research and Development Collaboration Agreement • December 30th, 2021 • Intrinsic Medicine, Inc. • Biological products, (no disgnostic substances) • Colorado

THIS RESEARCH AND DEVELOPMENT COLLABORATION AGREEMENT (the “Agreement”) made and entered into as of Dec 22, 2020 (the “Effective Date”), by and between ARPEGGIO BIOSCIENCES, INC. (“Arpeggio”) at [***] and INTRINSIC MEDICINE, INC. (“Intrinsic”) at [***], Arpeggio and Intrinsic are hereinafter referred to individually as a “Party” and jointly as “Parties.”

AMENDMENT NO. 1 LICENSE, CLINICAL SUPPLY AND PARTNERSHIP AGREEMENT BY AND BETWEEN GLYCOSYN, LLC AND INTRINSIC MEDICINE, INC. (FORMERLY KNOWN AS LUPA BIO, INC.)
License, Clinical Supply and Partnership Agreement • December 30th, 2021 • Intrinsic Medicine, Inc. • Biological products, (no disgnostic substances)

This AMENDMENT NO. 1 to the LICENSE, CLINICAL SUPPLY AND PARTNERSHIP AGREEMENT (the “Amendment No. 1”), effective as of January 21, 2021 (the “Effective Date”), between GLYCOSYN, LLC (“Glycosyn”), located at 95 Sawyer Road, Suite 120, Waltham, MA 02453 and INTRINSICE MEDICINE, INC. (“Intrinsic”), located at [***], Glycosyn and Intrinsic are hereinafter referred to individually as a “Party” and jointly as “Parties.”

AMENDMENT NO. 1 TO THE LICENSE AGREEMENT BETWEEN LUPA BIO, INC. AND THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
The License Agreement • December 30th, 2021 • Intrinsic Medicine, Inc. • Biological products, (no disgnostic substances) • California

This Amendment No. 1 to the License Agreement (this “Amendment No. 1”) is entered into by and between Lupa Bio, Inc. (hereinafter “LICENSEE”) and the Regents of the University of California (“UNIVERSITY”) represented by its San Diego campus (“UC San Diego”), each referred to herein as a “Party”, or collectively as the “Parties”. Capitalized terms used herein and not otherwise defined have the meanings ascribed to them in the License Agreement.

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