0000950123-20-009257 Sample Contracts

SILENCE THERAPEUTICS PLC AND THE BANK OF NEW YORK MELLON As Depositary AND OWNERS AND HOLDERS OF AMERICAN DEPOSITARY SHARES Deposit Agreement
Deposit Agreement • August 20th, 2020 • Silence Therapeutics PLC • Pharmaceutical preparations • New York

DEPOSIT AGREEMENT dated as of __________, 2020 among SILENCE THERAPEUTICS PLC, a company incorporated under the laws of England and Wales (herein called the Company), THE BANK OF NEW YORK MELLON, a New York banking corporation (herein called the Depositary), and all Owners and Holders (each as hereinafter defined) from time to time of American Depositary Shares issued hereunder.

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LICENSE AND COLLABORATION AGREEMENT* by and between SILENCE THERAPEUTICS PLC and MALLINCKRODT PHARMA IP TRADING DAC Dated as of July 18, 2019
License and Collaboration Agreement • August 20th, 2020 • Silence Therapeutics PLC • Pharmaceutical preparations

THIS LICENSE AND COLLABORATION AGREEMENT is made and entered into effective as of July 18, 2019 (the “Effective Date”) by and between

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RESEARCH COLLABORATION, OPTION AND LICENSE AGREEMENT* by and between
License and Collaboration Agreement • August 20th, 2020 • Silence Therapeutics PLC • Pharmaceutical preparations

THIS LICENSE AND COLLABORATION AGREEMENT (“Agreement”) is made and entered into effective as of March 24, 2020 (the “Effective Date”) by and between

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