0000950123-13-010600 Sample Contracts

SECURITY AGREEMENT
Security Agreement • December 24th, 2013 • Aquinox Pharmaceuticals (Usa) Inc • Pharmaceutical preparations • British Columbia

AQUINOX PHARMACEUTICALS INC., a Canadian corporation incorporated under the federal laws of Canada and having its chief executive office at Suite 430, 5600 Parkwood Way, Richmond, British Columbia V6V 2M2

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LOAN AGREEMENT
Loan Agreement • December 24th, 2013 • Aquinox Pharmaceuticals (Usa) Inc • Pharmaceutical preparations • British Columbia

THIS LOAN AGREEMENT (this “Agreement”) dated as of October 23, 2013 (the “Effective Date”) between SILICON VALLEY BANK, a California corporation (“Bank”), and AQUINOX PHARMACEUTICALS INC., a Canadian federal corporation (“Borrower”), provides the terms on which Bank shall lend to Borrower and Borrower shall repay Bank. The parties agree as follows:

SECURITY AGREEMENT
Security Agreement • December 24th, 2013 • Aquinox Pharmaceuticals (Usa) Inc • Pharmaceutical preparations • California

This Security Agreement (this “Agreement”) is entered into as of October 23, 2013, by and between SILICON VALLEY BANK (“Bank”) and AQUINOX PHARMACEUTICALS (USA) INC., a Delaware corporation (“Pledgor”).

AMENDMENT NO. 2 TO SHAREHOLDERS’ AGREEMENT
Shareholders’ Agreement • December 24th, 2013 • Aquinox Pharmaceuticals (Usa) Inc • Pharmaceutical preparations • British Columbia

THIS AMENDMENT NO. 2 TO SHAREHOLDERS’ AGREEMENT (this “Agreement”) is dated for reference as of November 18, 2013 among Aquinox Pharmaceuticals Inc. (the “Canadian Company”), Aquinox Pharmaceuticals (USA) Inc. (the “U.S. Company”) and certain shareholders of the Canadian Company and U.S. Company identified as such on the signature page thereto (the “Shareholders”).

Contract
Assignment Agreement • December 24th, 2013 • Aquinox Pharmaceuticals (Usa) Inc • Pharmaceutical preparations • California

THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR THE SECURITIES LAWS OF ANY STATE AND, EXCEPT AS SET FORTH IN SECTIONS 5.3 AND 5.4 BELOW, MAY NOT BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED UNLESS AND UNTIL REGISTERED UNDER SAID ACT AND LAWS OR IN FORM AND SUBSTANCE SATISFACTORY TO THE COMPANY, SUCH OFFER, SALE, PLEDGE OR OTHER TRANSFER IS EXEMPT FROM SUCH REGISTRATION.

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