0000950123-11-015543 Sample Contracts

Exhibit B LOCK-UP LETTER AGREEMENT
Lock-Up Letter Agreement • February 18th, 2011 • MPM BioVentures IV QP LP • Pharmaceutical preparations

BARCLAYS CAPITAL INC. PIPER JAFFRAY & CO. As Representatives of the several Underwriters named in Schedule I of the Underwriting Agreement, c/o Barclays Capital Inc. 745 Seventh Avenue New York, New York 10019

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