0000950120-07-000173 Sample Contracts

PLEDGE AGREEMENT
Pledge Agreement • March 2nd, 2007 • Biospecifics Technologies Corp • Pharmaceutical preparations • New York

This PLEDGE AGREEMENT (this “Agreement”), effective as of the 1st day of January 2007 by and between THE S.J. WEGMAN COMPANY (the “Pledgor”) and BIOSPECIFICS TECHNOLOGIES CORP., a Delaware corporation (the “Secured Party”).

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Contract
Agreement • March 2nd, 2007 • Biospecifics Technologies Corp • Pharmaceutical preparations

AGREEMENT made as of the 1st day of October, 1993, by and between MARTIN K GELBARD, MD., 2601 W. Alameda Ave, Burbank, CA 91505, hereinafter referred to as “Dr. Gelbard”, and ADVANCE BIOFACTURES CORPORATION, 35 Wilbur Street, Lynbrook, N.Y. 11563, hereinafter referred to as “the Company”.

Amendment No. 1 to DEVELOPMENT AND LICENSE AGREEMENT
Development and License Agreement • March 2nd, 2007 • Biospecifics Technologies Corp • Pharmaceutical preparations

THIS AMENDMENT NO. 1 TO THE DEVELOPMENT AND LICENSE AGREEMENT (“Amendment No. 1”) is entered into by and between Auxilium Pharmaceuticals, Inc., a company incorporated under the laws of Delaware with offices at 160 W. Germantown Pike, Norristown, PA 19401 and its Affiliate (collectively, “Auxilium”) and BioSpecifics Technologies Corp. a company organized and existing under the laws of the State of Delaware with offices located at 35 Wilbur Street, Lynbrook, New York 11563 and its Affiliates (collectively, “BTC”).

EXTENSION AND MODIFICATION AGREEMENT
Extension and Modification Agreement • March 2nd, 2007 • Biospecifics Technologies Corp • Pharmaceutical preparations

This Extension and Modification Agreement is made and entered into this 1st day of July, 2005, by and between WILBUR ST. CORP. (“hereinafter referred to as Landlord”) and ADVANCED BIOFRACTURES CORP. and BIOSPECIFICS TECHNOLOGY CORP. (“hereinafter referred to as Tenant”).

AMENDMENT #1 TO RIGHTS AGREEMENT
Rights Agreement • March 2nd, 2007 • Biospecifics Technologies Corp • Pharmaceutical preparations • New York

AMENDMENT #1 TO RIGHTS AGREEMENT, dated as of June 19, 2003, (the “Agreement”), between BioSpecifics Technologies Corp., a Delaware corporation (the “Corporation”), and OTC Corporate Transfer Service Company, a sole proprietorship (the “Rights Agent”).

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