0000936392-05-000355 Sample Contracts

NEUROCRINE BIOSCIENCES, INC. EMPLOYMENT COMMENCEMENT NONSTATUTORY STOCK OPTION
Employment Commencement Nonstatutory Stock Option • November 1st, 2005 • Neurocrine Biosciences Inc • Biological products, (no disgnostic substances) • California

THIS EMPLOYMENT COMMENCEMENT NONSTATUTORY STOCK OPTION (the “Agreement”), dated as of October 31, 2005, is made by and between Neurocrine Biosciences, Inc., a Delaware corporation (the “Company”), and Christopher O’Brien, M.D., an employee of the Company (the “Optionee”).

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