0000920148-10-000110 Sample Contracts

LABORATORY CORPORATION OF AMERICA HOLDINGS as Issuer AND as Trustee FIRST SUPPLEMENTAL INDENTURE DATED AS OF NOVEMBER 19, 2010
Indenture • November 19th, 2010 • Laboratory Corp of America Holdings • Services-medical laboratories • New York

FIRST SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated as of November 19, 2010 between Laboratory Corporation of America Holdings, a Delaware corporation (or its permitted successor) (the “Company”), and U.S. Bank National Association, as Trustee under the Indenture (the “Trustee”).

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LABORATORY CORPORATION OF AMERICA HOLDINGS ISSUER AND U.S. BANK NATIONAL ASSOCIATION INDENTURE DATED AS OF NOVEMBER 19, 2010 SENIOR DEBT SECURITIES
Supplemental Indenture • November 19th, 2010 • Laboratory Corp of America Holdings • Services-medical laboratories • New York

INDENTURE, dated as of November 19, 2010, between LABORATORY CORPORATION OF AMERICA HOLDINGS, a Delaware corporation (the “Company”), and U.S. BANK NATIONAL ASSOCIATION, a national banking association, as trustee (the “Trustee”):

Laboratory Corporation of America Holdings $325,000,000 3.125% Senior Notes Due 2016 $600,000,000 4.625% Senior Notes Due 2020 Underwriting Agreement
Laboratory Corp of America Holdings • November 19th, 2010 • Services-medical laboratories • New York

Laboratory Corporation of America Holdings, a corporation organized under the laws of Delaware (the “Company”), proposes to sell to the several underwriters named in Schedule II hereto (the “Underwriters”), for whom you (the “Representative”) are acting as representative, the principal amount of its notes identified in Schedule I hereto (the “Notes”), to be issued under an indenture (the “Indenture”) dated as of November 19, 2010, between the Company and U.S. Bank National Association, as trustee (the “Trustee”). To the extent there are no additional Underwriters listed on Schedule I other than you, the term Representative as used herein shall mean you, as Underwriter, and the terms Representative and Underwriters shall mean either the singular or plural as the context requires. Any reference herein to the Registration Statement, the Base Prospectus, any Preliminary Prospectus or the Final Prospectus shall be deemed to refer to and include the documents incorporated by reference therei

LABORATORY CORPORATION OF AMERICA HOLDINGS as Issuer AND as Trustee SECOND SUPPLEMENTAL INDENTURE DATED AS OF NOVEMBER 19, 2010
Second Supplemental Indenture • November 19th, 2010 • Laboratory Corp of America Holdings • Services-medical laboratories • New York

SECOND SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated as of November 19, 2010 between Laboratory Corporation of America Holdings, a Delaware corporation (or its permitted successor) (the “Company”), and U.S. Bank National Association, as Trustee under the Indenture (the “Trustee”).

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