0000912057-02-010801 Sample Contracts

FIRST AMENDMENT TO THE COLLABORATION, LICENSE AND ROYALTY AGREEMENT BETWEEN
License and Royalty Agreement • March 21st, 2002 • Collateral Therapeutics Inc • Biological products, (no disgnostic substances)

This first amendment (“Amendment”) to the Collaboration, License and Royalty Agreement dated May 6, 1996 (“Agreement”) made between Schering Aktiengesellshaft (“Parent”) and Collateral Therapeutics, Inc. (the “Company”) is made this 19th day of March, 2002 (the “Effective Date”).

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Contract
Stockholders Agreement • March 21st, 2002 • Collateral Therapeutics Inc • Biological products, (no disgnostic substances) • Delaware

STOCKHOLDERS AGREEMENT dated as of March 19, 2002 (this “Agreement”), among SCHERING AKTIENGESELLSCHAFT, a stock corporation organized under the laws of the Federal Republic of Germany (“Parent”), and the individuals and other parties listed on Schedule A attached hereto (each, a “Stockholder” and, collectively, the “Stockholders”).

AMENDMENT TO RIGHTS AGREEMENT
Rights Agreement • March 21st, 2002 • Collateral Therapeutics Inc • Biological products, (no disgnostic substances) • Delaware

WHEREAS, in connection with the execution of the Agreement and Plan of Merger, dated as of the date of this Amendment, by and among Schering AG, a stock corporation organized under the laws of the Federal Republic of Germany (the "Parent"), European Acquisition Company, a Delaware corporation and a wholly owned subsidiary of Parent (the "Sub"), and the Company, the board of directors of the Company has approved and adopted this Amendment rendering the Rights Agreement inapplicable to the Merger Agreement (as defined below), the Stockholders Agreement (as defined below) and the transactions contemplated by the Merger Agreement and the Stockholders Agreement.

AGREEMENT AND PLAN OF MERGER Dated as of March 19, 2002 Among SCHERING AKTIENGESELLSCHAFT, EUROPEAN ACQUISITION COMPANY And COLLATERAL THERAPEUTICS, INC.
Agreement and Plan of Merger • March 21st, 2002 • Collateral Therapeutics Inc • Biological products, (no disgnostic substances) • Delaware

AGREEMENT AND PLAN OF MERGER (this “Agreement”) dated as of March 19, 2002, among SCHERING AKTIENGESELLSCHAFT, a stock corporation organized under the laws of the Federal Republic of Germany (“Parent”), EUROPEAN ACQUISITION COMPANY, a Delaware corporation and a wholly owned subsidiary of Parent (“Sub”), and COLLATERAL THERAPEUTICS, INC., a Delaware corporation (the “Company”).

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