0000891618-06-000004 Sample Contracts

CONNETICS CORPORATION NON-QUALIFIED STOCK OPTION AGREEMENT
Non-Qualified Stock Option Agreement • January 10th, 2006 • Connetics Corp • Pharmaceutical preparations • California

Connetics Corporation, a Delaware corporation (“Connetics” or the “Corporation”), hereby grants to Brian Davis (the “Optionee”) an option to purchase 12,000 shares of Common Stock (the “Option”) subject to the following terms and conditions of this Non-Qualified Stock Option Agreement (the “Option Agreement”):

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CONNETICS CORPORATION NON-QUALIFIED STOCK OPTION AGREEMENT
Non-Qualified Stock Option Agreement • January 10th, 2006 • Connetics Corp • Pharmaceutical preparations • California

Connetics Corporation, a Delaware corporation (“Connetics” or the “Corporation”), hereby grants to David Burch (the “Optionee”) an option to purchase 10,000 shares of Common Stock (the “Option”) subject to the following terms and conditions of this Non-Qualified Stock Option Agreement (the “Option Agreement”):

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